Transfusion-Associated Graft-vs-Host Disease
نویسندگان
چکیده
منابع مشابه
Transfusion Associated Graft versus Host Disease
Case 1: A five-year-old girl, a case of acute lymphoblastic leukemia (L1) presented with fever and lethargy a fortnight after receiving the late intensification chemotherapy consist-ing of vincristine, daunorubicin, cytarabine, etoposide, thioguanine and oral dexamethasone over a period of five days (UK ALL X protocol)(8). She had been in a sustained first remission for nearly 18 weeks. Examina...
متن کاملTransfusion-associated graft-versus-host disease
Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare but almost uniformly lethal complication of blood transfusion. Although the graft-versus-host disease (GVHD) that occurs after allogeneic bone marrow transplantation and TA-GVHD share some clinical similarities, GVHD after bone marrow transplant is not uncommon and often responds positively to immunosuppression. The much rarer...
متن کاملTransfusion-associated graft-versus-host disease.
Transfusion associated graft versus host disease (TA-GVHD) results from engraftment of viable donor T-lymphocytes in recipient that can not recognize or destroy them. It is seen in immunocompromised patients and pre-mature neonates. It can also occur in immunocompetent individuals receiving blood from first-degree relatives. It has emerged as single most common cause of death resulting from tra...
متن کاملTransfusion-associated graft-versus-host disease
Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare complication of transfusion of cellular blood components producing a graft-versus-host clinical picture with concomitant bone marrow aplasia. The disease is fulminant and rapidly fatal in the majority of patients. TA-GvHD is caused by transfused blood-derived, alloreactive T lymphocytes that attack host tissue, including bone ...
متن کاملColumnar epidermal necrosis: a unique manifestation of transfusion-associated cutaneous graft-vs-host disease.
BACKGROUND In 1978, the first case of columnar epidermal necrosis was reported in a 6-year-old boy. There were scaly, partially vesicular or crusty, erythematous lesions mainly involving the extremities that histopathologically showed peculiar features of focal, total epidermal necrosis accompanied by a lichenoid tissue reaction. He developed the skin eruption after receiving a blood transfusio...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2000
ISSN: 1943-7722,0002-9173
DOI: 10.1309/qe5g-n5qx-gqwx-n04m